Epigenomic drivers of immune dysfunction in aging
نویسندگان
چکیده
منابع مشابه
Disease drivers of aging.
It has long been known that aging, at both the cellular and organismal levels, contributes to the development and progression of the pathology of many chronic diseases. However, much less research has examined the inverse relationship-the contribution of chronic diseases and their treatments to the progression of aging-related phenotypes. Here, we discuss the impact of three chronic diseases (c...
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Inflammatory processes play a critical role in the pathogenesis of the neurodegenerative disorders and are associated with cognitive impairments. Nonsteroidal anti-inflammatory drugs (NSAIDs) and nitric oxide releasing NSAIDs are reported to be effective in reducing the risk of developing AD or cognitive impairments. Present experiments were performed to study the possible effect of nitro napro...
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ژورنال
عنوان ژورنال: Aging Cell
سال: 2018
ISSN: 1474-9718,1474-9726
DOI: 10.1111/acel.12878